Out of Patients
with Matthew Zachary
Welcome to 2026: The Year of the Patient where the sick shall inherit the ballot.
52 Years Old and Still Here
Brain cancer at 21 forced Matthew Zachary into the American healthcare system decades before he understood its economics, incentives, and failures. At 52, he reflects on how surviving long enough to see the whole machine clearly led to writing We the Patients.
The Healthcare System Works Exactly as Designed. Cancer Patients Pay the Price.
Cancer patients increasingly absorb the financial risk of surviving disease in America. A brain cancer survivor examines how healthcare incentives, insurance design, and policy decisions shifted instability onto patients and families while institutions protect margins.
Out of Patients EP445: Fatal to Relentless: Kathy Giusti
Patients now need executive level skills to survive diagnosis, treatment, and access. This essay featuring Kathy Giusti breaks down how healthcare incentives create that reality, who benefits, who pays, and what must change to reduce risk and restore accountability.
MZLIVE and the Accidental Creation of America’s Survivorship Movement
Thirty years after brain cancer, Matthew Zachary returned to the piano at Merkin Hall for MZLIVE, a night that became far more than a concert. Survivors, advocates, clinicians, and healthcare leaders confronted what survivorship actually costs and what the system still refuses to see
Today My Book Comes Out! It's Already In Its Second Printing. That Never Happens.
We the Patients officially launches today and is already in its second printing before release day. Matthew Zachary shares why readers across healthcare, advocacy, and survivorship circles are responding so strongly to a book that names the realities patients live through every day.
How I’d Spend $1 Billion to Fix Healthcare Alongside Mark Cuban
Mark Cuban attacks healthcare through pricing transparency and market discipline. I would attack it through patient infrastructure, legal protection, accountability, and civic power. Together, those strategies could finally begin realigning the incentives driving American healthcare.
When Patients Stop Trusting Dermatology
Millions of eczema patients increasingly distrust the treatments medicine tells them to rely on. Matthew Zachary examines topical steroid withdrawal, chronic inflammation, patient distrust, and the healthcare incentives driving one of medicine’s fastest growing credibility crises
The National Health Council Is Hosting A Conference On AI And Patient Advocacy. There Are Zero Patients On The Panel.
A conference on patient advocacy with zero patients on the panel says everything. The industry keeps explaining itself while excluding the people who live the consequences. Here is what that looks like and why it keeps happening.
It's A Bird. It's A Plane. It's A Book Trailer! 🙀
After 30 years inside the healthcare system, Matthew Zachary watches his story and thousands of others come to life in a cinematic trailer for We the Patients and explains why this project now reaches far beyond a book.
An ICU Doctor Checked His Insurance Portal Every Day While His Daughter Was Dying Of Cancer. He Was Terrified They Would Kick Her Off.
Dr. Hesham Hassaballa is board certified four times over with 20 years in the ICU. When his daughter was getting chemo, he checked his insurance portal daily, terrified they would drop her. A physician. In the system. Earning a good living. Still terrified of financial ruin because his child got sick.
Prior Authorization Works Exactly as Designed and That Is the Problem
Prior authorization persists because it works for the system that created it. This essay explains how cost control, risk management, and delay shape patient outcomes, why reform keeps falling short, and what must change to align financial incentives with timely care.
What Happens If More Patients Appeal Insurance Denials?
Only 0.2% of patients appeal insurance denials, yet 80% succeed. This article examines how even small increases in appeals could shift insurer behavior, raise costs, influence Wall Street expectations, and reshape the economics of American healthcare.
This Week In Cuban: Our Patron Saint Is Still Doing The Lord’s Work.
Mark Cuban is stepping in where insurers fail, funding care and challenging the system. But real change will not come from policy alone. A unified patient voting bloc could reshape healthcare power in America.
I went on Humanity Rx to say the quiet part clearly and attach names, timelines, and consequences to it.
Matthew Zachary joins Humanity Rx to break down how modern cancer care improves survival while leaving patients exposed to medical debt, prior authorization delays, and financial risk, and why policy change depends on organized patient power.
Healthcare Is a Private Tax Triggered by Diagnosis
Gallup reports 82 million Americans cut back on daily life to afford healthcare. Coverage shifts financial risk to families through deductibles and prior authorization. Diagnosis now operates like a private tax on survival and forces tradeoffs across work, housing, and retirement.
[EVENT] Matthew Zachary Returns to the Stage | 30 Year Cancerversary LIVE in NYC 4/28
After 22 years away from solo performance, Matthew Zachary returns to the stage April 28 at Merkin Concert Hall in NYC. A live piano concert marking 30 years since brain cancer, featuring stories from the cancer community and the launch of We the Patients.
Eczema, Exit, Repeat: The Business Model of Chronic Disease
Millions cycle through eczema treatments that calm symptoms but never fix the cause. This essay explains how payment models, regulation, and product marketing keep patients trapped in repeat care instead of long term prevention.
An Open Letter (Again) to Mark Cuban on Behalf of American Patients
Mark Cuban walked into the Senate with spreadsheets and receipts. He called PBMs a cartel. He saved Medicare $2 billion. But math doesn't show up at town halls. Receipts don't vote. Here's the hole in his equation and an invitation to fix it.
Mark Cuban Wants to Take Us Back To 1955
Mark Cuban exposes PBM corruption and champions transparent drug pricing. He is right about generics. He is wrong about cash solving catastrophic care. A brain cancer survivor explains why $12 prescriptions and $960,000 transplants live in different universes.
Out of Patients EP432: Callus on Your Soul: Jenny Opalinski
Jenny Opalinski worked ICU floors where 10 to 15 traumatic events can hit in a single shift. In EP432 of Out of Patients she confronts clinician burnout, moral injury, and the cost of empathy in healthcare. A raw conversation about survival inside a system that grinds people down.